We are pleased to announce that the (almost) complete OpenTox Euro 2018 Conference Program with speaker abstracts is now available on our website. We are still accepting posters:  http://www.opentox.net/submit-abstract-poster-or-chair

Celebrating 10 years of open science, the WikiPathways team, a collaboration between the Bioinformatics department at Maastricht University and Alex Pico’s group at Gladstone, is hosting a 3-day summit on pathway tools, resources and research, featuring seminars and hands-on workshops. The summit is free to attend and will be held at Gladstone Institutes in San Francisco from October 8-10, 2018.

EU-ToxRisk was represented at the 18th International Conference on (Q)SAR in Environmental and Health Sciences (QSAR 2018), which took place from 11-15 June in Bled, Slovenia. It is a great pleasure for the project to announce that, Domenico Gadaleta and Cosima Toma, both from the EU-ToxRisk partner Mario Negri (IRFMN), won the Taylor & Francis award for the best posters presented by students for their posters “R and KNIME integration for QSAR development of Plasma Protein Binding” and “Exploiting ToxCast data to develop structure-activity relationships (QSAR) for molecular initiating events of adverse outcome pathways leading to hepatic steatosis”. Both posters referred to work realised within the EU-ToxRisk project.

For more information about the conference, please follow this link.


The EU-ToxRisk project and Joint Research Centre (JRC) have agreed to collaborate in the field of chemical safety assessment with the general objective of providing an effective interface between the research activities and regulatory aspects and to translate the research results into validated test methods and strategies fit for regulatory purpose.


The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) is conducting a survey to assess stakeholders' opinion on the scientific and technical issues that influence end-user confidence and uptake of complex in vitro models (e.g. 3D cell cultures, organ-on-chip, microphysiological systems). The survey can be accessed here: https://ec.europa.eu/eusurvey/runner/VCIVM2017

The deadline for completing the survey is Thursday 31st May 2018. It should not take more than about 15-20 min to complete it.

EURL ECVAM would be very grateful if you could distribute this survey within your organisation/network so that your colleagues can also have a word.

Thank you for your time responding to the questionnaire. Your opinion is highly appreciated.

EU-ToxRisk represented at the SOT 2018

- San Antonio, USA

EU-ToxRisk was present again at the annual SOT meeting in San Antonio, which took place from the 11th until the 15th of March 2018. EU-ToxRisk members organized and participated in two scientific sessions on read-across approaches and mitochondrial toxicity, respectively. In addition, there was an EU-ToxRisk satellite meeting “EU-ToxRisk: 2 year Review and Outlook” which was very well attended. For the duration of the conference EU-ToxRisk also maintained a booth, where interested parties could find out more information about the project.

You can find more information about the SOT 2018 on the event's website. 

The third issue of the EU-ToxRisk Newsletter (February 2018) is now available.

Please click here to access the electronic version of the document.

We hope you will enjoy the read.

The second issue of the EU-ToxRisk Newsletter (August 2017, No.2) has now been released.

You can download the document here.

We hope you will have a good read.

Cosmetics Europe Science Conference 2017

- The Bloom Hotel, Brussels

The Cosmetics Europe Science Conference is an exceptional event that aims to facilitate dialogue between scientists and regulators interested in novel approaches to cosmetics products and ingredients safety assessment.

Over 150 attendees from across Europe and the globe will meet in Brussels to participate in multidisciplinary seminars and plenary sessions, engage in lively debates and network.

You can now register on the Cosmetics Europe conference 2017 website.

For more information on the event, please contact the Science Conference Team

This workshop, organized by CAAT, brought together about 20 selected experts from academia, industry and regulatory bodies for a 2.5 day meeting involving intellectual exchange, brainstorming and conceptual work in an atmosphere of openness and objectivity.

It intended to bring experts in field of DART, including relevant EUToxRisk partners (e.g. BASF SE), to discuss functionality and fitness-for-purpose of promising non-animal DART approaches from academic, industrial and regulatory points of view.

The first EU-ToxRisk workshop on data handling took place on 27-28 April 2017 in Konstanz, Germany.
The event intended to implement an understanding of the importance to having data stored in a consistent and useful format.

EU-ToxRisk represented at the SOT 2017

- Baltimore, USA

The EU-ToxRisk consortium was represented at the SOT 2017 which was held on 12-16 March 2017 in Baltmore, USA. A joint discussion took take place with representatives from Tox21.

You can find more information about the SOT 2017 on the event's website.

The first issue of the EU-ToxRisk Newsletter (February 2017, No.1) is now available.

Please click here to access the electronic version of the document.

The first EU-ToxRisk Winter School was held on 20-21 February 2017, in Sitges, Spain. This was followed by the third EU-ToxRisk General Assembly (GA) meeting on the 22nd-24th February.

The EU-ToxRisk consortium was represented at the EC Conference in response to the Citizen Initiative “Stop Vivisection”, which took place on the 6th-7th December 2016 in Brussels. Members of the EU-ToxRisk consortium were not only be presenting during the event but there was also an EU-ToxRisk booth to raise further awareness of the project, alongside other like-minded EU-funded research projects, such as the SEURAT-1 initiative.

EU-ToxRisk at ECVAM/PARERE workshop

- Ispra, Italy

Members of the EU-ToxRisk consortium presented at the recent ECVAM/PARERE workshop in Ispra, Italy (9th-10th November 2016). In particular, the EU-ToxRisk participants showcased the work undertaken and progress achieved with regards to the case studies.


The EU-ToxRisk project and the Toxicology in the 21st Century (Tox21) initiative in the US have agreed to collaborate on efforts to reduce the use of animals and achieve more efficient chemical safety assessments.

A total of 28 representatives from both projects gathered in a workshop held in Mainz (Germany) on the 12th-14th September 2016 to initiate collaboration across areas of mutual interest within the field of risk assessment.

You can find further information in the EU-ToxRisk-Tox21 joint Press Release.

EU-ToxRisk AOP workshop

- Vienna, Austria

The EU-ToxRisk AOP workshop took place from the 19th-22nd September at the University of Vienna. The aim of the workshop was to initiate the building of a set of AOPs for the EU-ToxRisk project and to ensure that these AOPs are built in consideration of the different EU-ToxRisk case studies. Participants involved PIs, Postdocs and Ph.D. students working on the project, while experts from the OECD, the RIVM, the EPA, the University of Vienna and the JRC were providing the workshop training activities.

The workshop report is available here.

EU-ToxRisk-Tox21 Joint Workshop

- Mainz, Germany

The EU-ToxRisk-Tox21 joint workshop will take place on 13-14 September 2016 in Mainz, Germany. The workshop will bring together the Principal Investigators from both projects to discuss areas of practical cooperation, complementarity and exchange, particularly with regard to the work performed in the case studies and in terms of specific Work Package activities.



- Seville, Spain

Members of the EU-ToxRisk consortium presented their latest research findings at the EUROTOX conference in Seville, Spain (4th-7th September 2016). A dedicated EU-ToxRisk panel was planned, where the participating members of the consortium had the opportunity to disseminate information regarding the project.

EU-ToxRisk 2016 first Summer School and second General Assembly meeting

- Egmond aan Zee, the Netherlands

First EU-ToxRisk Summer School was held between the 27th and the 29th June 2016, in the Dutch seaside resort of Egmond aan Zee. This was followed by the second EU-ToxRisk General Assembly (GA) meeting on the 29th June until the 1st July. The third EU-ToxRisk GA meeting is planned for February 2017.

EU-ToxRisk Participation in ECHA Workshop

- Helsinki, Finland

EU-ToxRisk members participated in the ECHA workshop held in Helsinki, Finland on 19-20 April 2016.

EU-ToxRisk Participation in New Orleans SOT Event

- New Orleans

EU-ToxRisk members participated in this month’s SOT meeting held in New Orleans, LA, from the 13th-17th March 2016.

This workshop presented and discussed the new Good Read-across Practice guidance and other current initiatives for the benefit of past and future REACH registrants. Key speakers included EU-ToxRisk consortium members such as CAAT’s Thomas Hartung and Marcel Leist from the University of Konstanz. The topics cover the 2016 Good Read-across practice guidance, Ambit tool, Seurat-1 case studies, EU-ToxRisk, and the ECHA Read-across Assessment Framework (RAAF).

You can find more information here.